Endocrine Abstracts

Background: Hashimoto’s Thyroiditis (HT) is the most common clinical expression of thyroid dysfunction and result from organ-specific autoimmune reaction. Cytokines are play an important role in autoimmunity, by stimulating B and T cells.The aim of this study is to examine the relationship between cytokines and thyroid function tests in patient with Hashimoto’s ThyroiditisMethods: 139 cases with HT included this study. Su...

Background: Hashimoto’s thyroiditis (HT) is a common autoimmune disease of thyroiditis. There is a relation with Vitamin D levels, vitamin D receptor (VDR) and HT reported. More than 30 gene polymorphisms are found in VDR gene. The most common four types of polymorphisms studied in autoimmune disease are FokI (exon 2), BsmI (intron 8), ApaI (intron 8) and TaqI (exon 9). The aim of this study is to investigate the association between VDR TaqI gene polymorphism and HT subty...

Background: Hashimoto’s thyroiditis is the most common autoimmune endocrine disorders and often leads to hypothyroidism. There is a relation with Vitamin D levels, vitamin D receptor (VDR) and HT reported. More than 30 gene polymorphisms are found in VDR gene. The most common four types of polymorphisms studied in autoimmune disease are FokI (exon 2), BsmI (intron 8), ApaI (intron 8) and TaqI (exon 9). The aim of this study is to investigate the association between VDR Fo...

Background: Hashimoto’s thyroiditis (HT) is one of the most common autoimmune thyroiditis that characterised by lymphocytic infiltration and thyroid hormonal disturbances. Genetic and environmental factors play a role in etiology of the disease, but genetic factors are most common. In this study, we investigated the association between Hashimoto’s thyroiditis and IL-2, IL-4, IL-5, TNF-α and IFN-γ levels.Methods: We performed a case&#1...